abstract：:Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. This study evaluated the pharmacokinetics and biodistribution of 99Tcm(V)DMSA in patients with SCC and calculated the bone mass of a New Zealand White (N...

journal_title：Nuclear medicine communications

authors： Watkinson JC,Allen S,Lazarus CR,Sinclair J,Blake GM,Clarke SE

更新日期：1990-05-01 00:00:00

abstract：:To evaluate 201Tl in the detection of the primary tumour, lymph node involvement and mediastinal spread we have studied a total of 188 patients with histologically proven lung cancer, breast cancer or malignant lymphoma. Ten patients with benign lung disease were also examined. Static images were performed 20 min afte...

journal_title：Nuclear medicine communications

authors： Sehweil AM,McKillop JH,Milroy R,Sayed MA,Ziada G,Banham SW,Davidson KG,Ragib A,Omar YT,Abdel-Dayem HM

更新日期：1990-04-01 00:00:00

abstract：:Thirty patients with aortic valve incompetence and 21 control subjects were examined by M-mode echocardiography at rest and radionuclide ventriculography during submaximal handgrip exercise. The patients had greater left ventricular dimensions and end-systolic wall stress values but peak systolic wall stress values di...

journal_title：Nuclear medicine communications

authors： Groundstroem K,Huikuri H,Korhonen U,Ikäheimo M,Heikkilä J,Torniainen P,Linnaluoto M,Takkunen J

更新日期：1990-04-01 00:00:00

abstract：:In 70 patients with angiographically confirmed coronary heart disease and in 10 controls, a 4 h exercise (E) (injection of 150 MBq 99Tcm-MIBI) rest (R) (800 MBq) protocol was employed. Of these, 10 patients with 21 myocardial defects after E received a third injection 24 h after. SPECT was used to image myocardial dis...

journal_title：Nuclear medicine communications

authors： Buell U,Dupont F,Uebis R,Kaiser HJ,Kleinhans E,Reske SN,Hanrath P

更新日期：1990-02-01 00:00:00

abstract：:Patients with acute arterial occlusion may suffer from significant muscle necrosis. It is important to determine the amount of regional muscle necrosis for prognostic purposes and evaluation of therapy. We have used technetium-99m-pyrophosphate (PPi) with single photon emission computed tomography (SPECT) to quantitat...

journal_title：Nuclear medicine communications

authors： Yip TC,Houle S,Hayes G,Forrest I,Nelson L,Walker PM

更新日期：1990-02-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：:We studied two different methods for the evaluation of differential renal function in a group of 100 patients with various kidney disorders whose effective renal plasma flow (ERPF) had been calculated previously by single 125I-orthoiodohippurate (OIH) injection and multiple blood sampling. Patients were divided into t...

journal_title：Nuclear medicine communications

authors： Llamas-Elvira JM,Martinez-Paredes M,Jimenez-Heffernan A,Sopena R,Requena MJ,Gonzalez FM,Torres M,Mateo A

更新日期：1989-10-01 00:00:00

abstract：:An examination of the biokinetics and biodistribution of i.p. administered 131I- or 111In-labelled 791T/36 antibody (1 mg) has been carried out in five patients with stage III/IV ovarian cancer. Blood kinetics and urinary excretion of the radiolabels were assayed. Scintigraphy was performed immediately following admin...

journal_title：Nuclear medicine communications

authors： Perkins AC,Pimm MV,Gie C,Marksman RA,Symonds EM,Baldwin RW

更新日期：1989-08-01 00:00:00

abstract：:The biodistribution of two stereoisomeric 99Tcm complexes derived from diastereomeric dimercaptosuccinic acids (DMSA), 99Tcm-dl-DMSA and 99Tcm-meso-DMSA, was examined in sarcoma 180 tumour-bearing mice. The biodistribution pattern of meso-complex was not significantly different from 99Tc(V)m-DMSA, a new tumour imaging...

journal_title：Nuclear medicine communications

authors： Awh OD,Kim JR,Shim SC

更新日期：1989-06-01 00:00:00

abstract：:Right ventricular performance was assessed in 37 patients with acute myocardial infarction within two hours of admission to Coronary Care and compared to results in 21 normal volunteers and 12 patients undergoing coronary arteriography. Right ventricular ejection fraction (RVEF) was measured from gated xenon-133 scans...

journal_title：Nuclear medicine communications

authors： Martin W,Tweddel A,McGhie I,Hutton I

更新日期：1989-01-01 00:00:00

abstract：:To assess the precision of gated equilibrium radioventriculography in measuring changes in left ventricular stroke volume (LVSV), we studied five dogs each with a chronically implanted electromagnetic flowmeter on the ascending aorta. Per cent changes in left ventricular stroke counts (LVSC) were compared to those in ...

journal_title：Nuclear medicine communications

authors： Valette H,Bourguignon MH,Apoil E,Moyse D,Wise RA,Buchanan JW,Wagner HN Jr,Syrota A

更新日期：1988-12-01 00:00:00

abstract：:Since 99Tcm-DTPA is diffusible and not significantly protein bound in plasma, it rapidly enters the extravascular space following injection. Therefore, during the first few minutes of the DTPA renogram, the period on which the measurements of individual kidney glomerular filtration rate and differential function are b...

journal_title：Nuclear medicine communications

authors： Peters AM,George P,Ballardie F,Gordon I,Todd-Pokropek A

更新日期：1988-12-01 00:00:00

abstract：:The use of 111In-labelled granulocyte scintigraphy is recognized as a reliable method for detecting osteomyelitis and has similar sensitivity and significantly increased specificity compared to bone scintigraphy and 67Ga studies. Recent published work using pure granulocytes labelled with 111In tropolonate to detect o...

journal_title：Nuclear medicine communications

authors： Roddie ME,Peters AM,Osman S,Danpure HJ,Lavender JP,Neirinckx RD

更新日期：1988-10-01 00:00:00

abstract：:Following injection for renography, 99Tcm-labelled diethylenetriamine-pentacetic acid (DTPA) rapidly enters the extravascular space. Background therefore comprises two components, a falling intravascular signal and an extravascular signal which initially rises. We estimated the relative magnitudes of these two compone...

journal_title：Nuclear medicine communications

authors： Peters AM,Gordon I,Evans K,Todd-Pokropek A

更新日期：1988-08-01 00:00:00

abstract：:Monoclonal antibody (MoAb) fragments are known to have advantages over intact immunoglobulins for radioimmunoscintigraphy. It is less clear whether they are as effective in the delivery of radioimmunotherapy. The imaging and dosimetric properties of an intact MoAb, K-1-21, reactive against human kappa light chains (LC...

journal_title：Nuclear medicine communications

authors： Walker KZ,Seymour-Munn K,Towson JE,Axiak SM,Raison RL,Bautovitch GJ,Morris J,Basten A

更新日期：1988-07-01 00:00:00

abstract：:Scintigraphically, Warthin's tumour usually demonstrates increased tracer uptake compared to normal adjacent salivary tissue. A case is presented in which tumour uptake is no greater than the normal adjacent gland. Gustatory stimulation results in failure of tumour tracer washout, and this finding rather than 'hot' sa...

journal_title：Nuclear medicine communications

authors： Blue PW

更新日期：1988-06-01 00:00:00

abstract：:Ion-exchange resin beads, implanted into connective tissue, were used as the vehicle for the delivery of radiolabelled cations to determine the local distribution of lead, silver and cadmium in loose connective tissue. The system was devoid of systemic toxicity, permitted a predictable release, enabled location of rel...

journal_title：Nuclear medicine communications

authors： Ellender G,Ham KN

更新日期：1988-06-01 00:00:00

abstract：:We performed in vitro aggregation and indium-111 labeled platelet kinetic and biodistribution studies in seven patients with diabetes mellitus and in five control subjects. All subjects were male. All diabetic patients were poorly controlled at the time of study with blood glucose greater than 140 mg % and hemoglobin ...

journal_title：Nuclear medicine communications

authors： Luikens B,Forstrom LA,Johnson T,Johnson G

更新日期：1988-03-01 00:00:00

abstract：:Morphine sulfate has been used by several investigators in the cholescintigraphic diagnosis of acute cholecystitis. A review of the available literature indicates that morphine sulfate significantly reduces the total time required for the hepatobiliary examination, while retaining both high sensitivity (98.8%) and spe...

journal_title：Nuclear medicine communications

authors： Vasquez TE,Rimkus DS,Pretorius HT,Greenspan G

更新日期：1988-03-01 00:00:00

abstract：:Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...

journal_title：Nuclear medicine communications

authors： Nishimura T,Uehara T,Hayashida K,Nagata S

更新日期：1988-01-01 00:00:00

abstract：:Measurements were made of the concentration of radioactivity in the breast milk of two patients: one following 100 MBq (2.7 mCi) 99Tcm-pertechnetate administration, and the other following administration of 550 MBq (15 mCi) 99Tcm-glucoheptonate. The fractional activity concentrations in the former case were about two ...

journal_title：Nuclear medicine communications

authors： Mountford PJ,Coakley AJ

更新日期：1987-10-01 00:00:00

abstract：:In order to perform automatically the thresholding of the amplitude image obtained by phase analysis, a filter based on the probability density of the amplitude is proposed. It generates the image of the significant amplitude by setting to zero the amplitude if its square is lower than 4a0 log(1/alpha)/N where a0 is t...

journal_title：Nuclear medicine communications

authors： Liehn JC,Valeyre J

更新日期：1987-10-01 00:00:00

abstract：:Radioactive tracer techniques using 131I- and 125I-insulin have been applied to study insulin metabolism. A simple method to label human insulin with 123I to a high specific activity is described. We have used this radiotracer to study insulin kinetics in vivo in normal subjects and in two groups of diabetic patients....

journal_title：Nuclear medicine communications

authors： Sinclair AJ,Signore A,Bomanji J,Britton KE,Pozzilli P,Gale EA

更新日期：1987-10-01 00:00:00

abstract：:Micturating renograms often need to be carried out on children, with whom difficulty may be experienced in synchronizing onset of micturition with camera and computer acquisition. A flow detection system has been developed which will automate these acquisitions, resulting in far fewer false starts or lost studies. The...

journal_title：Nuclear medicine communications

authors： Burniston MT,Royall RA,Tapper RC

更新日期：1987-09-01 00:00:00

abstract：:A non-invasive technique for the assessment of hepatic haemodynamics using radiocolloid imaging with a computer, in which absolute values of hepatic, mesenteric and splenic arterial effective blood flows were assessed, is described. The technique was carried out on ten volunteers, before and after a standard meal. Aft...

journal_title：Nuclear medicine communications

authors： Walmsley BH,Fleming JS,Ackery DM,Karran SJ

更新日期：1987-08-01 00:00:00

abstract：:Radiolabeled sucralfate has been utilized by several investigators to evaluate peptic ulcer, active inflammatory bowel disease, esophageal ulcer, and gastric cancer. A review of the available literature indicates that radiolabeled sucralfate has been used to evaluate peptic ulcer and active inflammatory bowel diseases...

journal_title：Nuclear medicine communications

authors： Vasquez TE,Pretorius HT,Greenspan G

更新日期：1987-05-01 00:00:00

abstract：:Reticuloendothelial system (RES) phagocytic function or capacity can be measured by clearance studies with test substances. This study in the rat examines three commercially available 99Tcm-labelled test substances, and different methods of calculating RES capacity. Albures size 500 nm and sulphur colloid size 600 nm ...

journal_title：Nuclear medicine communications

authors： Holmberg SB,Hafström L,Jacobsson L

更新日期：1987-05-01 00:00:00

abstract：:The influence of zooming on centre-of-rotation (COR) of the rotating camera-based SPECT system and on the resolution of tomographic images was investigated. COR values were measured as a function of zoom factor varying from x1.0 to x3.0. Measurements were performed using two SPECT systems collimated with three collima...

journal_title：Nuclear medicine communications

authors： Saw CB,Clarke LP,Serafini AN

更新日期：1987-01-01 00:00:00

abstract：:To evaluate the incidence, severity and clinical course of right ventricular (RV) involvement after acute inferior myocardial infarction (IMI), 78 patients (pts) with IMI were investigated by both 99Tcm-pyrophosphate (PYP) scan and gated blood pool scan (GBPS). GBPS was performed at admission and 10 days, whereas 99Tc...

journal_title：Nuclear medicine communications

authors： Nishimura T,Yasuda T,Gold HK,Leinbach RC,Boucher CA,McKusick KA,Strauss HW

更新日期：1986-12-01 00:00:00

abstract：:Sodium iodide (131I) capsules are widely used for both diagnosis and therapy. The radiochemical purity of both diagnostic and therapeutic capsules in use in Australia was studied by gel chromatography, high voltage electrophoresis and paper chromatography. It was found that in two of the three bands of therapeutic cap...

journal_title：Nuclear medicine communications

authors： Bonnyman J,Van Every B

更新日期：1986-11-01 00:00:00

abstract：:Conventional nuclear medicine methods for measuring glomerular filtration rate, GFR, are invalidated if the initial injection of radiopharmaceutical is tissued. An analytical method proposed by Veall and Gibbs in 1982 overcomes this difficulty but does require multiple blood samples. This paper investigates whether it...

journal_title：Nuclear medicine communications

authors： Casey M,Barker F,Duffy G

更新日期：1986-11-01 00:00:00

abstract：:The biodistribution of 131I-6 beta-iodomethyl-19-norcholesterol (NP-59) was assessed in hypercholesterolaemic patients and in a rabbit model of HC to examine the alterations in the relative distribution of NP-59 and its metabolites and to explain the changes in the patterns of adrenal cortical imaging in patients with...

journal_title：Nuclear medicine communications

authors： Lynn MD,Gross MD,Shapiro B,Bassett D

更新日期：1986-08-01 00:00:00

abstract：:Twelve patients with a diagnosis of schizophrenia and thirteen control subjects were injected with 77Br-bromospiperone and scanned using single photon emission tomography after 16 h. Although a statistically significant increase in patients by comparison with controls could be demonstrated, wide variations in specific...

journal_title：Nuclear medicine communications

authors： Crawley JC,Crow TJ,Johnstone EC,Oldland SR,Owen F,Owens DG,Smith T,Veall N,Zanelli GD

更新日期：1986-08-01 00:00:00

abstract：:21 patients with Wolff-Parkinson-White (WPW) syndrome were investigated through radionuclide imaging and body surface mapping. Ventricular preexcitation was localized by display of identical phase ventricular regions (phase display). In 79% of the cases radioisotope and body surface mapping methods have identical resu...

journal_title：Nuclear medicine communications

authors： Mester J,Préda I,Kozmann G,Máté E,Regös L,Tóth K,Marosi G,Antalóczy Z,Csernay L

更新日期：1986-07-01 00:00:00

abstract：:The study of the kinetics of labelled platelets makes sense only when the platelets preserve their viability after separation and labelling. The separation and labelling procedures described in the manual of two producers of 111In-oxinate (Amersham, Mallinckrodt) have been evaluated by in vitro aggregation tests. The ...

journal_title：Nuclear medicine communications

authors： Mortelmans L,Verbruggen A,De Roo M,Vermylen J

更新日期：1986-07-01 00:00:00

abstract：:Left ventricular ejection fractions (EF) were measured with a nuclear stethoscope (NSt, beat-to-beat and ECG gated summation method) and contrast ventriculography (VG) immediately following one another (IFOA) (r X 0.96 and 0.95, respectively, n = 13). NSt and ECG gated gamma camera (MUGA) recordings IFOA were compared...

journal_title：Nuclear medicine communications

authors： Lund O,Rasmussen K,Jensen FT,Hansen HH

更新日期：1986-05-01 00:00:00

abstract：:Radically operated tumour patients (gastrointestinal cancer, n = 10; lung cancer, n = 10) were subjected to continuous prospective monitoring of the serum level of tissue polypeptide antigen (TPA) prior to surgical treatment as well as during the subsequent year. The following observations were made: Immediately after...

journal_title：Nuclear medicine communications

authors： Bauer T,Muhrer KH,Müller H,Grebe SF

更新日期：1986-02-01 00:00:00

abstract：:Forty-four patients with symptoms of lower limb arterial insufficiency were examined by radionuclide angiography using 99Tcm in vivo red cell labelling and by contrast aortography. The results of the study indicate that radionuclide angiography may well have a useful role to play in determining the type of contrast st...

journal_title：Nuclear medicine communications

authors： Grime JS,Critchley M,Whitehouse GH,Zavras G

更新日期：1986-01-01 00:00:00

abstract：:To study the accuracy of renal function quantification with 99Tcm-DMSA we compared DMSA renal uptake and creatinine clearance in 16 cases of children with single kidney. The age of the patients ranged from two months to fourteen years. Creatinine clearance was normalized to 1.73 m2. DMSA uptake was measured 7 h after ...

journal_title：Nuclear medicine communications

authors： Baillet G,Gagnadoux MF,De Vernejoul P,Broyer M

更新日期：1985-11-01 00:00:00

abstract：:The uptake of 123I-5-iodo-2-thiouracil in melanotic and amelanotic melanoma implanted in Syrian golden hamsters was studied. A selective accumulation was found in the tumours. Uptake of 123ITU in melanotic melanomas was 4 to 5 times the uptake in amelanotic ones. For both tumours high ratios of tumours versus non-tumo...

journal_title：Nuclear medicine communications

authors： Franken NA,Van Langevelde A,Journée-De Korver JG,Bakker CN,Feitsma RI,Van Delft JL,Oosterhuis JA,Pauwels EK

更新日期：1985-10-01 00:00:00